Mauricio Pellegrino has been overseeing Saints' penultimate training session today as preparation steps up for the Brighton clash, before speaking about the availability of his squad this afternoon.
The manager confirmed that summer signing Mario Lemina has been ruled out of the weekend's Premier League action, following an ankle injury sustained in training, with no time frame put on his return.
The rest of the squad has been given a clean bill of health, while Pellegrino is also considering the inclusion of young forward Sofiane Boufal after his match-winning contribution against West Brom.
"Mario Lemina is injured this week," the boss began. "He is the only player we'll lose this week."
"Sofiane is one possibility from the start, in the last two or three games he is playing well, even from the bench.
"I am happy with that, I want to improve the competition in the squad. Sofiane is a young lad and this action can give him more confidence to be better."