Southampton will travel to Sky Bet League 1 side Sheffield United in the Capital One Cup quarter-finals.
After seeing off Stoke City in Round 4 this evening, Saints were the last team out of the hat when the fifth-round draw was made.
Having already recorded away wins over Millwall, Arsenal and now Stoke in the competition, Ronald Koeman's men will once again go on the road as they head to Bramall Lane in the week commencing Monday 15th December.
This is the first time Saints have reached the quarter-final stage of the League Cup since 2003/04, and this will be the first meeting between the two sides since the 2008/09 Championship season.
A confirmed date and ticketing details for this match will be announced in due course.